Sema. + Cagrilintide is a dual-peptide research blend designed to investigate the synergistic effects of GLP-1 receptor activation and amylin receptor modulation. Sema. functions as a GLP-1 receptor agonist that supports glucose-dependent insulin secretion, reduces glucagon release, and slows gastric emptying. Cagrilintide is a long-acting amylin analogue that activates amylin and calcitonin receptors, further influencing satiety signaling, gastric emptying, and metabolic regulation.

Together, these peptides provide researchers with a powerful model for studying complementary hormonal pathways involved in appetite regulation, energy balance, weight management, and glycemic control.